OK. "wiped out" is perhaps an extreme description. The Aztecs and Myans were of South America were "wiped out". I have seen some documentaries that have said this. The North American, Native peoples/tribes were not totally "wiped out". However I don't think "impacted" goes far enough. When estimates hover between 1/3 to 1/2 of the total population of Europe died off because of the plague, "impacted" doesn't quite cut it. In a similar vein the peoples in North America were cut down for centuries. Maybe "devastated" would be a better word.
With many Native American's gone so too does much knowledge of this animal. Some legends are still recalled by people who survive but how much more info is lost to us as different tribes were killed off? Maybe there were some which had better information/more detailed legends and are now gone.
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